Based on his daily diary entries that provide a vivid and accurate picture of events, the author candidly recounts his development as a merchant mariner from his early years as an indentured apprentice on the Elysia, followed by two years sailing on a passenger ship to India before the Second World War erupted. At sea the war news is relayed in bits and pieces, feeding the underlying tension that keeps rising to the surface. Daily life is punctuated by terrifying episodes such as seeing ships sunk in convoy or hearing bombs drop beside the ship when in port during heavy air raids and the author also relates the horrific experience of being torpedoed. The extremes of nature that all on board had to contend with - winter storms on the North Atlantic; navigating in convoy through flow ice and avoiding icebergs; fog and the ever-present danger of collision; the extreme heat experienced in the Red Sea and Persian Gulf, without air conditioning - are all accurately described. He also relates the problems encountered when sailing on worn-out ships that would normally have been scrapped had it not been for the war, and as a consequence experiencing leaks, engine trouble and bursts of flame spouting from the funnel in areas where submarines were operating! There are glimpses of the author's moods and thoughts, sometimes funny, sometimes poignant and sometimes romantic. He displays a droll sense of humour and there are interesting philosophical comments dotted throughout the book. On a return to peacetime sailing, the author was an officer on cargo ships, qualifying as a Master Mariner before he left the sea. "School of the Sea" is a treasure house of unusual information, the kind not usually included in history books. It's personal, vivid, and entertaining and contains some wonderful descriptions of the dramas and mundane routines of shipboard society; stays in foreign ports; when on leave and the long sequestered life at sea. So much is missing from some existing maritime literature on WWII, where the focus is mainly on danger, excitement and death - this book, like no other, captures every dimension of daily life at sea and in port.

Richard Jones's production of Benjamin Britten's most popular opera takes to the stage at the Teatro alla Scala in Milan. John Graham-Hall stars as the eponymous, impetuous fisherman in this mysterious tale set in a small fishing village on England's east coast in the 19th century. Robin Ticciati, principal conductor of the Scottish Chamber Orchestra, takes the helm in his La Scala opera debut.

"Embracing Destiny's Crossroads" is: The unveiling of the author's real life journey that goes beyond her autobiography in revealing simple life's lessons on what to do when reaching crossroads in your life.

Articular cartilage is a unique and highly specialized avascular connective tissue in which the availability of oxygen and glucose is significantly lower than synovial fluid and plasma. Glucose is an essential source of energy during embryonic growth and fetal development and is vital for mesenchymal cell differentiation, chondrogenesis and skeletal morphogenesis. Glucose is an important metabolic fuel for differentiated chondrocytes during post-natal development and in adult articular cartilage and is a common structural precursor for the synthesis of extracellular matrix glycosaminoglycans. Glucose metabolism is critical for growth plate chondrocytes which participate in long bone growth. Glucose concentrations in articular cartilage can fluctuate depending on age, physical activity and endocrine status. Chondrocytes are glycolytic cells and must be able to sense the concentration of oxygen and glucose in the extracellular matrix and respond appropriately by adjusting cellular metabolism. Consequently chondrocytes must have the capacity to survive in an extracellular matrix with limited nutrients and low oxygen tensions. Published data from our laboratories suggest that chondrocytes express multiple isoforms of the GLUT/SLC2A family of glucose/polyol transporters. In other tissues GLUT proteins are expressed in a cell-specific manner, exhibit distinct kinetic properties, and are developmentally regulated. Several GLUTs expressed in chondrocytes are regulated by hypoxia, hypoxia mimetics, metabolic hormones and pro-inflammatory cytokines. In this multidisciplinary article we review the molecular and morphological aspects of GLUT expression and function in chondrocytes and their mesenchymal and embryonic stem cell precursors and propose key roles for these proteins in glucose sensing and metabolic regulation in cartilage.